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Compressed air requirements for pharmaceutical enterprises

2026-04-15Views:

Pharmaceutical Enterprises Compressed Air Core Requirements Gelanklin Water Lubricated Air Compressor Adaptability Description

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1. Pharmaceutical Industry Compressed Air Core Requirements

in the production process of pharmaceutical enterprises, compressed air directly contacts drugs or is used for power drive in clean areas, and its quality must meet the following strict standards:

  1. Oil-free purity
    The content of oil (including liquid oil, oil mist and oil vapor) in compressed air shall be ≤ 0.01 mg/m & sup3;. Oil may breed bacteria, contaminate drugs, cause batch scrap or threaten patient health. For example, in the filling process of aseptic preparations, oily air may destroy the sterility of the drug product.

  2. Low humidity and stable dew
    point The pressure dew point of compressed air shall be ≤-40 ℃ to avoid pipeline corrosion, instrument failure or moisture absorption and deterioration of drugs caused by water condensation. For example, in the powder conveying process, moisture may cause material agglomeration, affecting the continuity of production.

  3. Microorganism and particle control
    The number of microorganisms in compressed air should be <1CFU/m & sup3;(sterile drugs) or <10CFU/m & sup3;(non-sterile drugs), and the particle size of solid particles should be ≤ 0.1 μm. Microbial contamination may alter the efficacy of the drug, and particulate matter may damage equipment or affect the appearance of the product.

  4. compressed air without peculiar smell and harmful gases
    shall be colorless and tasteless, and the content of harmful gases such as carbon monoxide shall be <5 mg/m & sup3;, so as to avoid potential risks to the health of operators or the quality of drugs.

2. Grankering Water Lubricated Single Screw Air Compressor Technical Adaptability

granklin water-lubricated single-screw air compressor uses water as the lubricating medium through the technology of single screw and star wheel meshing compression to eliminate oil pollution from the source and accurately match the core demand of the pharmaceutical industry for compressed air:

  1. Zero oil pollution ensures purity
    . The water lubrication compression method completely eliminates oil droplets, oil mist and oil vapor that may be generated by the oil lubrication system. The oil content of the output compressed air approaches 0, which is far lower than the standard limit of 0.01 mg/m & sup3 in the pharmaceutical industry to ensure the safety of drug production.

  2. Efficient water removal and stable dew point control
    The equipment has built-in multi-stage drying and filtering system, which can stably output dry air with pressure dew point ≤-40 ℃ and effectively prevent moisture condensation. For example, in the fermentation tank ventilation process, dry air can avoid abnormal cell metabolism and improve fermentation efficiency.

  3. Multi-stage filtration to remove microorganisms and particles
    The compressed air can remove particles and microorganisms ≥ 0.01μm through three-stage treatment of pre-filtration, fine filtration and sterilization filtration, and meet the compressed air quality requirements of clean area A (high-risk operation area) to D (low-risk operation area) in the pharmaceutical industry.

  4. Environmental protection design and low operation risk
    The equipment adopts low noise and low vibration design, and the operation noise is less than 70 decibels, which reduces the interference to the clean area environment. The water lubrication system does not need consumables such as oil separator, which reduces maintenance cost and shutdown risk and ensures production continuity.

3. Grankering air compressor in the pharmaceutical industry typical application scenarios

    1. Aseptic preparation production
      In the process of vial filling and freeze-dried powder needle preparation, granklin air compressor provides oil-free and sterile compressed air to ensure that the sterility of drugs meets GMP standards and avoid batch scrapping due to air pollution.

    2. the fermentation process supports
      that in the fermentation process of antibiotics, vitamins, etc., the equipment outputs compressed air with stable pressure and purity to provide sufficient oxygen for microorganisms, while avoiding oil to inhibit cell activity or moisture to interfere with fermentation parameters.

    3. Powder conveying and packaging
      in powder conveying, capsule filling and other links, dry oil-free compressed air can prevent material agglomeration or equipment blockage, improve packaging efficiency and product qualification rate.

  • 4. Conclusion

    the pharmaceutical industry has stringent requirements for the purity, dryness and microbiological control of compressed air. Granklin water-lubricated single screw air compressor provides pharmaceutical companies with GMP-compliant compressed air solutions through core technologies such as oil-free compression, high-efficiency water removal and multi-stage filtration, helping companies achieve drug quality improvement, production efficiency optimization and green manufacturing goals.

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