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Quality standard of compressed air for biological fermentation

2026-04-14Views:

Biological fermentation has strict requirements on the quality of compressed air to ensure the smooth progress of the fermentation process and the output of high-quality products. The following is a detailed summary of the biological fermentation compressed air quality standards:

1. pressure (pressure)

the biological fermentation industry has clear requirements on the pressure of compressed air to ensure that the compressed air maintains a stable pressure during transportation and use. Generally speaking, the air pressure at the outlet of the air compressor is controlled 0.2 to 0.35MPa (gauge pressure) or 0.2 to 0.4MPa. This range can ensure that the compressed air meets the needs of the bio-industrial production process, while avoiding the high air pressure at the compressor outlet, saving power consumption and reducing production costs.

2. flow

the flow rate of compressed air is calculated based on the total fermenter volume of the fermentation plant or fermentation plant. Typically, the required compressed air flow rate is determined by the aeration ratio of the pilot plant or VVM (volume of air per unit volume of culture medium per unit time under standard conditions). Ensure continuity and stability in the production process.

3. temperature

the temperature of the air entering the fermenter needs to be 10-30°C higher than the fermentation temperature. This requirement helps to maintain the stability and efficiency of the fermentation process.

4. humidity

the relative humidity of the compressed air entering the total filter should be controlled between 60% and 70%. A suitable humidity helps to maintain optimal conditions for the biological reaction.

5. cleanliness

the fermentation process requires extremely high sterile air, and the compressed air must be sterile, dust-free, impurity-free, water-free, oil-free and maintain positive pressure. Cleanliness is usually required to reach 100 level, I .e. the maximum allowable number of dust particles (≥ 0.5 μm) is 3500 per cubic meter of air, and the maximum allowable number of microorganisms is 5 floating bacteria/m & sup3; And 1 settling bacteria/m & sup3;. In addition, there are also specific standards for the content of suspended particles, oil and water. For example, the concentration of suspended particles should meet the standard of Class D clean area or higher, and the oil content should be ≤ 0.1 mg/m & sup3;, moisture should meet the Grade 2 standard of GB/T13277-1, dew point ≤-40 ℃ (the corresponding absolute humidity value is 0.176 g/m & sup3;).

6. Sterility Requirements

sterile air used in fermentation plants requires strict control of multiple quality indicators. In addition to the above pressure, flow, temperature, humidity and cleanliness, it is also necessary to ensure that the compressed air is sterile. This is usually achieved through high-efficiency air filtration systems, such as the use of filter media such as polytetrafluoroethylene, and periodic sterilization.

In summary, the standard of compressed air quality by biological fermentation involves pressure, flow, temperature, humidity, cleanliness and sterility requirements. Together, these standards ensure the smooth running of the biofermentation process and the output of high-quality products.

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