Compressed air is widely used in pharmaceutical factories. It plays a vital role and is a key factor to ensure drug quality and production efficiency. The following are the main uses of compressed air in pharmaceutical plants:
1. pharmaceutical production equipment power source
- filling machines in liquid preparations: Compressed air provides power for the filling machine to ensure accurate filling of medicines.
- Equipment in solid preparations: In granulating machines, pulping machines, filling machines, packaging machines, printing machines and other equipment, compressed air is used for purging, conveying, drying and other processes. For example, compressed air plays a dynamic role in the capsule filling machine, and the filled capsules are discharged in time to prevent the filling process from being interrupted due to the untimely discharge.
- Extraction tank in extraction process: Compressed air provides power for the extraction tank, which is convenient for slag discharge and extraction process.
2. pharmaceutical production and environmental cleaning
- traditional Chinese medicine grinder, rotary tablet press, capsule polishing machine and other equipment compressed air plays the role of purging, which can remove dust and impurities in time to keep the equipment clean and the production environment sanitary.
- Ultrasonic bottle washing machine: Compressed air provides power to completely remove impurities in the bottle.
- Pneumatic conveyor belt: Compressed air drives the operation of packaging machinery, such as sealing machines, packaging machines, etc.
3. Drug Quality Control and Experiment
- test pilot gas in the process of drug testing, compressed air is used as test gas to ensure the accuracy of test results.
- New Drug Development and Research in R & D and laboratories in the pharmaceutical industry, compressed air can be used to supply experimental equipment, such as gas chromatographs, mass spectrometers and freeze-drying instruments. In addition, compressed air can also be used for pneumatic tools, such as pneumatic needles and sprayers.
4. drug production safety guarantee
- chinese medicine sterilization device compressed air provides a sealed environment for the sterilization process, so that the sterilization effect is better, so as to ensure the sterile state of the drug.
- Pneumatic instrumentation components and automatic control equipment: Many pneumatic instrument components and automatic control equipment need compressed air to drive to ensure the stability and controllability of the production process.
Special requirements for the production of 5. drugs
- oil-free, dry, dust-free, sterile because compressed air is in direct or indirect contact with drugs in pharmaceutical factories, it has extremely high requirements for its quality. The pharmaceutical factory must ensure that the content of oil, water, solid particles and biological particles in the compressed air is controlled at a very low level, and it is also required to be odorless. This is usually achieved through decontamination, validation and GMP certification checks.
Design of 6. compressed air system
- air purification treatment when the compressed air for medicine is transported to the point of use, it must go through the purification processes of cooling, degreasing, dewatering, removing solid dust particles, sterilization and filtration, etc., so as to meet the requirements of pharmaceutical production. For compressed air filtered by terminal sterilization, the number of microorganisms shall be <1cfu/m3.
- Pipeline Design the compressed air pipeline in the workshop of the pharmaceutical factory is generally laid overhead, and the main main pipes and branch pipes are all laid in the technical interlayer. In the sterile clean area, open pipes, risers and valves should be reduced as much as possible. The pipelines in the plant area can be laid overhead or directly buried, and anti-corrosion measures shall be taken according to the corrosion of the soil. Pipes and valve accessories are made of stainless steel materials, with 00 Cr17Ni14Mo2(316L) stainless steel material as the best.
To sum up, the application of compressed air in pharmaceutical factory is extensive and important. It is not only one of the main power sources in the drug production process, but also directly affects the quality and safety of drugs. Therefore, pharmaceutical companies must attach great importance to the quality and management of compressed air.
